Design & Analysis of Clinical Trials: Concepts & Methodologies 3/e [Chow] 9780470887653

The Third Edition of Design and Analysis of Clinical Trials provides complete, comprehensive, and expanded coverage of recent health treatments and interventions. Featuring a unified presentation, the book provides a well-balanced summary of current regulatory requirements and recently developed statistical methods as well as an overview of the various designs and analyses that are utilized at different stages of clinical research and development. 

頁數：896
版次：第3版
年份：2014年
規格：精裝/單色
ISBN：9780470887653

PART I PRELIMINARIES
1 Introduction
2 Basic Statistical Concepts
3 Basic Design Considerations
4 Randomization and Blinding
PART II DESIGNS AND THEIR CLASSIFICATIONS
5 Designs for Clinical Trials
6 Designs for Cancer Clinical Trials
7 Classification of Clinical Trials
PART III ANALYSIS OF CLINICAL DATA
8 Analysis of Continuous Data
9 Analysis of Categorical Data
10 Censored Data and Interim Analysis
11 Sample Size Determination
PART IV ISSUES IN EVALUATION
12 Issues in Efficacy Evaluation
13 Safety Assessment
PART V RECENT DEVELOPMENT
14 Biomarkers and Targeted Clinical Trials
15 Trials for Evaluating Accuracy of Diagnostic Devices
16 Statistical Methods in Translational Medicine
17 Adaptive Clinical Trial Designs
18 Traditional Chinese Medicine
PART VI CONDUCT OF CLINICAL TRIALS
19 Preparation and Implementation of a Clinical Protocol
20 Data Management of a Clinical Trial